En cliquant sur le bouton ci-dessous, vous pouvez consulter la liste des dernières publications scientifiques du laboratoire dans la "Collection HAL du M2P2" qui permet de faire des recherches par année, auteur, type de document (article scientifique, ouvrage, chapitre d'ouvrage, actes de conférence...), etc.
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Benjamin Bouillet, Romain Boulestreau, Victor Aboyans, Sophie Béliard, Franck Boccara, et al.. Management of dyslipidemia in adults. A consensus statement from the French Society of Endocrinology (SFE), the French-speaking Diabetes Society (SFD), the New French-speaking Atherosclerosis Society (NSFA) and the French Society of Cardiology (SFC). Diabetes & Metabolism, 2026, 52 (2), pp.101725. ⟨10.1016/j.diabet.2026.101725⟩. ⟨hal-05515709⟩ Plus de détails...
Benjamin Bouillet, Romain Boulestreau, Victor Aboyans, Sophie Béliard, Franck Boccara, et al.. Management of dyslipidemia in adults. A consensus statement from the French Society of Endocrinology (SFE), the French-speaking Diabetes Society (SFD), the New French-speaking Atherosclerosis Society (NSFA) and the French Society of Cardiology (SFC). Diabetes & Metabolism, 2026, 52 (2), pp.101725. ⟨10.1016/j.diabet.2026.101725⟩. ⟨hal-05515709⟩
Paul Chambonniere, Evita Dollon, Alexandra Dimitriades-Lemaire, Jean-François Sassi, Florian Delrue. Scalable model development of carbon photosynthetic assimilation and partitioning in a green microalga during nitrogen starvation. Bioresource Technology, 2026, 441, pp.133585. ⟨10.1016/j.biortech.2025.133585⟩. ⟨cea-05424045⟩ Plus de détails...
Lipid accumulation in green microalgae is induced by stresses (e.g. nitrogen starvation) which compromise photosynthetic activity resulting in significantly lower biomass productivity than under nutrient replete conditions. While algae photosynthetic growth has been well characterized and modelled under nutrient replete conditions, the loss of photosynthetic activity during nitrogen starvation lacks specific studies to determine suitable parameterisation. The loss of photosynthetic activity of the lipid-accumulating microalgae Chlorella vulgaris NIES 227 was studied under varying light intensities during nitrogen starvation. Partition of assimilated carbon between the different macromolecules pools (carbohydrates, lipids, and proteins) was concomitantly monitored. The results showed that the decrease of photosynthetic activity correlated well to the increase of cell C:N ratio $(R^2$ = 0,883, $N$=65) enabling to develop a model of microalgae growth and carbon partition under nitrogen starvation. Biomass dry-weight increase could be predicted with good accuracy ($R^2$ = 0,940, $N$ = 66), as total lipid and carbohydrate production could also be predicted with fair accuracy ($R^2$=0,841 and 0,618 respectively). The present study henceforth showed that modelling microalgae productivity based on photosynthetic activity inferred from local light intensity, as done in scalable models under nutrient replete conditions, may be extended to nitrogen starvation conditions and enabled the prediction of lipids and carbohydrates productivity. The model proposed should thus prove useful in optimizing photobioreactors design for the production of important energetic molecules based on light distribution knowledge.
Paul Chambonniere, Evita Dollon, Alexandra Dimitriades-Lemaire, Jean-François Sassi, Florian Delrue. Scalable model development of carbon photosynthetic assimilation and partitioning in a green microalga during nitrogen starvation. Bioresource Technology, 2026, 441, pp.133585. ⟨10.1016/j.biortech.2025.133585⟩. ⟨cea-05424045⟩
Benjamin Bouillet, Romain Boulestreau, Victor Aboyans, Sophie Béliard, Franck Boccara, et al.. Management of dyslipidemia in adults. A consensus statement from the French Society of Endocrinology (SFE), the French-speaking Diabetes Society (SFD), the New French-speaking Society of Atherosclerosis (NSFA) and the French Society of Cardiology (SFC). Annales d'Endocrinologie = Annals of Endocrinology, 2026, 87 (1), pp.102471. ⟨10.1016/j.ando.2025.102471⟩. ⟨hal-05577444⟩ Plus de détails...
Benjamin Bouillet, Romain Boulestreau, Victor Aboyans, Sophie Béliard, Franck Boccara, et al.. Management of dyslipidemia in adults. A consensus statement from the French Society of Endocrinology (SFE), the French-speaking Diabetes Society (SFD), the New French-speaking Society of Atherosclerosis (NSFA) and the French Society of Cardiology (SFC). Annales d'Endocrinologie = Annals of Endocrinology, 2026, 87 (1), pp.102471. ⟨10.1016/j.ando.2025.102471⟩. ⟨hal-05577444⟩
Journal: Annales d'Endocrinologie = Annals of Endocrinology
Benjamin Bouillet, Romain Boulestreau, Victor Aboyans, Sophie Béliard, Franck Boccara, et al.. Management of dyslipidemia in adults. A consensus statement from the French Society of Endocrinology (SFE), the French-speaking Diabetes Society (SFD), the New French-speaking Atherosclerosis Society (NSFA) and the French Society of Cardiology (SFC). Archives of cardiovascular diseases, 2026, ⟨10.1016/j.acvd.2026.01.001⟩. ⟨hal-05577436⟩ Plus de détails...
Benjamin Bouillet, Romain Boulestreau, Victor Aboyans, Sophie Béliard, Franck Boccara, et al.. Management of dyslipidemia in adults. A consensus statement from the French Society of Endocrinology (SFE), the French-speaking Diabetes Society (SFD), the New French-speaking Atherosclerosis Society (NSFA) and the French Society of Cardiology (SFC). Archives of cardiovascular diseases, 2026, ⟨10.1016/j.acvd.2026.01.001⟩. ⟨hal-05577436⟩
Jinhua Lu, Thomas Gregorczyk, Song Zhao, Pierre Boivin. Phase-field-based recursive regularized multiphase lattice Boltzmann model with a consistent pressure scheme. International Journal of Multiphase Flow, 2026, 195, pp.105500. ⟨10.1016/j.ijmultiphaseflow.2025.105500⟩. ⟨hal-05344425⟩ Plus de détails...
Multiphase lattice Boltzmann models with enhanced stability and no deviation terms.
• Consistent pressure scheme decoupled from density and viscosity variations.
• The proposed model shows superior numerical stablity and accuracy.
Jinhua Lu, Thomas Gregorczyk, Song Zhao, Pierre Boivin. Phase-field-based recursive regularized multiphase lattice Boltzmann model with a consistent pressure scheme. International Journal of Multiphase Flow, 2026, 195, pp.105500. ⟨10.1016/j.ijmultiphaseflow.2025.105500⟩. ⟨hal-05344425⟩
Benoît Péden, Pierre Boivin, Nicolas Odier. Large-Eddy Simulation of a 3D airblast injector using a diffuse interface four-equation model: effects of evaporation and combustion. Combustion and Flame, 2026, 285, pp.114771. ⟨10.1016/j.combustflame.2026.114771⟩. ⟨hal-05557933⟩ Plus de détails...
This work presents Large-Eddy Simulations of a three-dimensional airblast-type injector using a diffuse-interface Multi-Fluid approach. A four-equation model is employed, including a consistent phase transition solver and a thermodynamic closure suitable for evaporating and reacting flows. The influence of evaporation and combustion on the spray and flow dynamics is investigated through a comparative analysis of cold, evaporative, and reactive configurations. The method is first validated against reference results and known behavior for similar injector geometries. It is shown that the addition of evaporation significantly alters the liquid fuel distribution, particularly in the inner recirculation zone, while combustion further modifies both liquid and gaseous fuel fields due to temperatureinduced evaporation and fuel consumption. The reacting case exhibits typical flame features, including hollow cone structures and localized high-temperature zones near stoichiometric mixture fractions. These phenomena align well with expected flame behavior under airblast conditions. Phase transition and combustion also have a notable impact on the velocity field, with increased expansion and stronger recirculation induced by heat release. The proposed model captures these effects in a unified framework. Finally, the present multi-physics approach enables consistent and efficient simulation of multiphase, reactive sprays, providing physical insight into the coupled interaction between atomization, evaporation, and combustion. The method shows good numerical performance on the 3D injector, with a reduced computational time of 2.1 × 10 -5 s.mpi/node/it, which has no overcost compared to the Lagrangian reference model. The fully explicit treatment of the equation of state (NASG) ensures excellent robustness on complex geometries, while avoiding the iterative procedure required by cubic-type EoS. These numerical properties make the DIM suitable for industrial LES configurations involving evaporation and combustion, and further model development.
Benoît Péden, Pierre Boivin, Nicolas Odier. Large-Eddy Simulation of a 3D airblast injector using a diffuse interface four-equation model: effects of evaporation and combustion. Combustion and Flame, 2026, 285, pp.114771. ⟨10.1016/j.combustflame.2026.114771⟩. ⟨hal-05557933⟩
Marc Le Boursicaud, Jean-Louis Consalvi, Pierre Boivin. Prediction of hydrogen–ammonia blends autoignition. Combustion and Flame, 2026, 285, pp.114713. ⟨10.1016/j.combustflame.2025.114713⟩. ⟨hal-05469163⟩ Plus de détails...
The growing interest in hydrogen as an alternative energy vector has raised new technological challenges, in particular regarding its storage. This has motivated increasing attention to ammonia as a hydrogen carrier. In parallel, the use of hydrogen-ammonia blends as combustible fuels has attracted significant interest, as such mixtures can be easier to handle in some applications than pure hydrogen, while still enabling carbon-free combustion.In this context, the present study focuses on modeling the ignition of arbitrary gaseous hydrogen-ammonia-air blends. First, the minimal chemical description required to accurately capture the ignition delay of these mixtures is identified, revealing three main ignition regimes. Ignition delay formulas are then derived for these regimes by extending methods previously developed for pure hydrogen and syngas. The resulting ignition time expressions are subsequently combined into a unified formulation, valid across a wide range of pressures, temperatures, and fuel compositions. Finally, modifications to a recently published passive scalar model for CFD tools are introduced so as to accurately predict ignition events in hydrogen-ammonia-air mixtures while reducing computational cost. Novelty and
Marc Le Boursicaud, Jean-Louis Consalvi, Pierre Boivin. Prediction of hydrogen–ammonia blends autoignition. Combustion and Flame, 2026, 285, pp.114713. ⟨10.1016/j.combustflame.2025.114713⟩. ⟨hal-05469163⟩
Amani Briki, Milos Kacanski, Romain Irague, Audrey Soric. Coupling of biohydrogen and polyhydroxyalkanoates production processes for next-generation biorefineries: process design, optimization and perspectives. Bioprocess and Biosystems Engineering, 2026, ⟨10.1007/s00449-026-03325-7⟩. ⟨hal-05584464⟩ Plus de détails...
The management of organic waste is currently a crucial environmental and societal challenge. Integrating waste treatment with renewable energy production has emerged as promising strategy for reducing the carbon footprint within an energy decarbonization approach. In this context, hydrogen-based biorefineries have gained attention for their ability to convert organic waste into carbon-free energy source. Nevertheless, their large-scale application remains constrained by limited yields, mainly attributed to the synthesis of volatile fatty acids (VFAs) as metabolic by-products. This review focuses on coupling hydrogen (H2) production with polyhydroxyalkanoates (PHAs) production to enhance organic matter recovery and support bioeconomy implementation. A comprehensive description of the coupled process design constitutes the first component of this review, emphasizing the interdependence of feedstock, inoculum types and bioreactor configurations at each stage. Various organic wastes are demonstrated as effective substrates for dark fermentation while the VFAs produced during this stage serve as potential carbon source for PHAs production. The review critically discusses key optimization strategies for the H2/PHAs coupled process, including pretreatment methods application, transition phase management and operational parameters control. It also highlights viable coupling strategies resulting in higher carbon removal efficiency. Based on different life cycle and techno-economic analyses, different challenges in feedstock pretreatment, process efficiency and downstream processing are identified. To overcome these constraints, several perspectives are suggested, emphasizing the relevance of incorporating modelling, nanotechnology and genetic engineering approaches, for better monitoring the coupled process, enhancing its efficiency and thus improving its sustainability and economic feasibility for large-scale implementation.
Amani Briki, Milos Kacanski, Romain Irague, Audrey Soric. Coupling of biohydrogen and polyhydroxyalkanoates production processes for next-generation biorefineries: process design, optimization and perspectives. Bioprocess and Biosystems Engineering, 2026, ⟨10.1007/s00449-026-03325-7⟩. ⟨hal-05584464⟩
A. Fayet, Stéphane Mimouni, Luc Favre, Catherine Colin, Pierre Boivin, et al.. Modeling and numerical simulation of boiling flows: application and dataset release of the DEBORA experiment. International Journal of Heat and Mass Transfer, In press. ⟨hal-05571906⟩ Plus de détails...
Computational Fluid Dynamics (CFD) is widely used in nuclear engineering for safety related studies or for new design investigations. Co-developed by EDF, CEA, ASNR and Framatome, the NEPTUNE_CFD code is specialized in nuclear thermal-hydraulic applications allowing the simulation of two-phase flows on complex geometries. Recently, a new Heat Flux Partitioning (HFP) model has been proposed by Favre et al. [1] for a thorough description of the boiling phenomena, including, among others, the effect of wall sliding bubbles. However, an excessive increase in computation time follows the subsequent modeling improvement. This paper presents an optimization of the bubble sliding calculation returning to a reasonable computation time compatible with industrial applications. The newly developed model is then validated using NEPTUNE_CFD and compared to the DEBORA experimental data, featuring R12 coolant boiling flow within a characteristic non-dimensional scope of a Pressurized Water Reactor (PWR). The improvement in the wall temperature calculation is demonstrated by several simulations implementing the new HFP model. To support the community's validation and benchmarking efforts, the complete DEBORA experimental dataset is made publicly available for the first time as part of this work, provided under a CC BY 4.0 license. This contribution advances both modeling capabilities and data availability, promoting transparency and reproducibility in multiphase CFD for nuclear applications
A. Fayet, Stéphane Mimouni, Luc Favre, Catherine Colin, Pierre Boivin, et al.. Modeling and numerical simulation of boiling flows: application and dataset release of the DEBORA experiment. International Journal of Heat and Mass Transfer, In press. ⟨hal-05571906⟩
Journal: International Journal of Heat and Mass Transfer
Hugo Taligrot, Vivian Dam Quang, Sébastien Wurtzer, Mathias Monnot, Damien Chaudanson, et al.. Investigating the impact of low-pressure reverse osmosis membrane aging and heterogeneity on performance: A study of virus and microplastic retention. Separation and Purification Technology, 2025, 376, ⟨10.1016/j.seppur.2025.133924⟩. ⟨hal-05468499⟩ Plus de détails...
The increasing demand for freshwater, alongside increasing microplastics and persistent microbiological contaminants, is degrading water quality and highlighting the need for advanced treatment processes with better retention performance. Low-pressure reverse osmosis (LPRO) presents a promising solution for producing drinking water from freshwater, offering an optimal balance between water quality and production costs. However, uncertainties remain regarding the long-term evolution of these performance metrics, which are primarily based on data from reverse osmosis membranes used in seawater desalination. This study investigates the impact of membrane aging on LPRO performance and the role of membrane heterogeneity within a spiral-wound module. New and long-term aged membranes were compared in terms of permeability, salt retention, and virus retention, with additional analysis of microplastic retention. Natural membrane aging led to increased permeability and decreased salt retention, without affecting virus and microplastic retention, for which retention remained total across the tested coupons. Performance heterogeneity was observed depending on the position of the coupons within the module, with a more significant degradation at the beginning of the module and winding, likely due to mechanical effects associated with higher pressure and deformation. In contrast, coupons located at the end of the module and winding showed minimal performance impact. No impact was observed on virus and microplastic retention, which remained complete, confirming that viruses do not pass through an intact membrane but rather through membrane defects and seals. Autopsy of the LPRO modules revealed membrane defects (glue patches, minor and major folds) that affected membrane performance. In particular, the presence of apparent major folds led to significant performance degradation, with lower permeability and salt retention. The folds also caused the passage of viruses into the permeate, while microplastic retention remained unaffected. The virus passing through the permeate of an LPRO pilot would therefore be due to defects in the membrane and Orings of the modules.
Hugo Taligrot, Vivian Dam Quang, Sébastien Wurtzer, Mathias Monnot, Damien Chaudanson, et al.. Investigating the impact of low-pressure reverse osmosis membrane aging and heterogeneity on performance: A study of virus and microplastic retention. Separation and Purification Technology, 2025, 376, ⟨10.1016/j.seppur.2025.133924⟩. ⟨hal-05468499⟩
