Sequential-Dispersion PGSS process applied to lutein encapsulation at moderate temperatures: A solvent-free method for thermosensitive compound encapsulation
Sequential-dispersion PGSS (SD-PGSS) applied to polymer excipient processing.
• Solvent-free SD-PGSS applied to the elaboration of controlled release drug delivery systems. • Lutein encapsulation with biocompatible polymers for oral uptake in AMD mitigation. • Process yields up to 94% under moderate temperatures (38 and 45 • C). • Modulation of lutein release profile from solid formulation.
M. Schneider, Y. Masmoudi, C. Girard, F. Matonti, C. Olmière, et al.. Sequential-Dispersion PGSS process applied to lutein encapsulation at moderate temperatures: A solvent-free method for thermosensitive compound encapsulation. Journal of Supercritical Fluids, 2024, 207, pp.106186. ⟨10.1016/j.supflu.2024.106186⟩. ⟨hal-05042395⟩
Journal: Journal of Supercritical Fluids
Date de publication: 01-05-2024
Auteurs:
- M. Schneider
- Y. Masmoudi
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C. Girard
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F. Matonti
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C. Olmière
- E. Badens
