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Procédés et mécanique aux petites échelles PROMETHEE

Micro-objets déformables sous forçage hydrodynamique

Microfluidique et Procédés

Organisation des écoulements aux petites échelles

Séparations membranaires

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Présentation

L’équipe PROcédés et MEcanique aux petiTes écHEllEs (PROMETHEE) développe des compétences marquées relevant aussi bien de la mécanique des milieux continus que du génie des procédés  tout en combinant approche expérimentale et développement de théories et de modèles. L’originalité des études menées se décline selon plusieurs spécificités :

  • Echelle micro-nano d’observation et d’analyse qui évacue les problématiques liées à la turbulence (régime de Stokes) mais nécessite de considérer des aspects aux frontières de la discipline ;
  • Rôle prédominant des interfaces : interactions avec les parois solides à l’échelle nano (nano-tubes), interaction fluide-structure avec des membranes fluides ou polymérisée à l’échelle méso ;
  • Connexion avec les fluides complexes, la matière molle et les systèmes biologiques.

Sur le thème de la micro- et nano-fluidique, les objets d’étude, physico-chimiques (gouttes, capsules,…) et biologiques (vésicules, globules rouges,…), comprennent aussi les procédés intensifiés  d’encapsulation et de vectorisation par microréacteur, thèmes en plein essor. L’équipe développe également des outils de caractérisation de l’organisation aux petites échelles  comme le développement de simulations numériques pour rendre compte de la ségrégation obtenue au sein de milieux granulaires et la mise au point de méthode chimique de caractérisation des effets de micromélange (mélange à l’échelle moléculaire). A cela s’ajoute une activité de caractérisation et modélisation thermodynamique de milieux complexes.

Les outils numériques développés et mis en œuvre sont variés : intégrale de frontière, éléments finis, immersed boundary method, méthode Lattice Boltzman… 

+ Micro-objets déformables sous forçage hydrodynamique
+ Microfluidique et Procédés
+ Organisation des écoulements aux petites échelles
+ Séparations membranaires

Responsable

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Annuaire personnel permanent

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Doctorants, Post-Doctorants et CDD

  • Pablo CANAMAS
    Doctorant
    équipe Procédés et mécanique aux petites échelles
  • Sudip Kumar DAS
    Post Doctorant (Centrale Marseille)
    équipe Procédés et mécanique aux petites échelles
  • Varun PUTHUMANA
    Doctorant
    équipe Procédés et mécanique aux petites échelles
  • Charly TESCH
    Doctorant
    équipe Procédés et mécanique aux petites échelles
  • Gang WANG
    Doctorant
    équipe Procédés et mécanique aux petites échelles
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Publications de l'équipe

  • 2021
    Jinming Lyu, Paul G. Chen, G. Boedec, M. Leonetti, Marc Jaeger. An isogeometric boundary element method for soft particles flowing in microfluidic channels. Computers and Fluids, Elsevier, 2021, 214, pp.104786. ⟨10.1016/j.compfluid.2020.104786⟩. ⟨hal-02476945v2⟩ Plus de détails...

    An isogeometric boundary element method for soft particles flowing in microfluidic channels

    Understanding the flow of deformable particles such as liquid drops, synthetic capsules and vesicles, and biological cells confined in a small channel is essential to a wide range of potential chemical and biomedical engineering applications. Computer simulations of this kind of fluid-structure (mem-brane) interaction in low-Reynolds-number flows raise significant challenges faced by an intricate interplay between flow stresses, complex particles' in-terfacial mechanical properties, and fluidic confinement. Here, we present an isogeometric computational framework by combining the finite-element method (FEM) and boundary-element method (BEM) for an accurate prediction of the deformation and motion of a single soft particle transported in microfluidic channels. The proposed numerical framework is constructed consistently with the isogeometric analysis paradigm; Loop's subdivision elements are used not only for the representation of geometry but also for the membrane mechanics solver (FEM) and the interfacial fluid dynamics solver (BEM). We validate our approach by comparison of the simulation results with highly accurate benchmark solutions to two well-known examples available in the literature, namely a liquid drop with constant surface tension in a circular tube and a capsule with a very thin hyperelastic membrane in a square channel. We show that the numerical method exhibits second-order convergence in both time and space. To further demonstrate the accuracy and long-time numerically stable simulations of the algorithm, we perform hydrodynamic computations of a lipid vesicle with bending stiffness and a red blood cell with a composite membrane in capillaries. The present work offers some possibilities to study the deformation behavior of confining soft particles, especially the particles' shape transition and dynamics and their rheological signature in channel flows.
    Jinming Lyu, Paul G. Chen, G. Boedec, M. Leonetti, Marc Jaeger. An isogeometric boundary element method for soft particles flowing in microfluidic channels. Computers and Fluids, Elsevier, 2021, 214, pp.104786. ⟨10.1016/j.compfluid.2020.104786⟩. ⟨hal-02476945v2⟩
    Journal: Computers and Fluids
    Date de publication: 01-01-2021
    Auteurs:
    Liste des documents:
    Digital object identifier (doi): http://dx.doi.org/10.1016/j.compfluid.2020.104786
    Voir la publication sur Hal
  • 2020
    Cláudio Fonte, David Fletcher, Pierrette Guichardon, Joelle Aubin. Simulation of micromixing in a T-mixer under laminar flow conditions. Chemical Engineering Science, Elsevier, 2020, 222, pp.115706. ⟨10.1016/j.ces.2020.115706⟩. ⟨hal-02892241⟩ Plus de détails...

    Simulation of micromixing in a T-mixer under laminar flow conditions

    The CFD simulation of fast reactions in laminar flows can be computationally challenging due to the lack of appropriate sub-grid micromixing models in this flow regime. In this work, simulations of micromixing via the implementation of the competitive-parallel Villermaux/Dushman reactions in a T-micromixer with square bends for Reynolds numbers in the range 60–300 are performed using both a conventional CFD approach and a novel lamellae-based model. In the first, both the hydrodynamics and the concentration fields of the reaction species are determined directly using a finite volume approach. In the second, the hydrodynamic field from the CFD calculations is coupled with a Lagrangian model that is used to perform the chemical reactions indirectly. Both sets of results are compared with previously published experimental data and show very good agreement. The lamellar model has the advantage of being much less computationally intensive than the conventional CFD approach, which requires extremely fine computational grids to resolve sharp concentration gradients. It is a promising solution to model fast chemical reactions in reactors with complex geometries in the laminar regime and for industrial applications.
    Cláudio Fonte, David Fletcher, Pierrette Guichardon, Joelle Aubin. Simulation of micromixing in a T-mixer under laminar flow conditions. Chemical Engineering Science, Elsevier, 2020, 222, pp.115706. ⟨10.1016/j.ces.2020.115706⟩. ⟨hal-02892241⟩
    Journal: Chemical Engineering Science
    Date de publication: 01-08-2020
    Auteurs:
    Liste des documents:
    Digital object identifier (doi): http://dx.doi.org/10.1016/j.ces.2020.115706
    Voir la publication sur Hal
  • 2020
    Jiupeng Du, Nelson Ibaseta, Pierrette Guichardon. Generation of an O/W emulsion in a flow-focusing microchip: importance of wetting conditions and of dynamic interfacial tension. Chemical Engineering Research and Design, Elsevier, 2020, ⟨10.1016/j.cherd.2020.04.012⟩. ⟨hal-02799613⟩ Plus de détails...

    Generation of an O/W emulsion in a flow-focusing microchip: importance of wetting conditions and of dynamic interfacial tension

    6 To date, there is no information on the microfluidic emulsification of dibutyl adipate and 7 n-butyl acetate in water. Since these solvents are very suitable for microencapsulation by 8 interfacial polymerization, it is highly necessary to study the emulsification behavior of these 9 solvents in microchannel. This work shows that the microfluidic emulsification of these sol-10 vents in water may fail to obtain stabilized flow regimes. This is due to droplet coalescence 11 and wall wetting, even if a hydrophilic microchip is used. Hydrodynamic results show that 12 squeezing and dripping regimes are especially affected because of the wall wetting by the 13 dispersed phase. This difficulty can be circumvented by adding a surfactant (here Tween 14 80) into the aqueous phase. However, high surfactant concentrations (ten times the crit-15 ical micelle concentration) should be used for the water-dibutyl adipate system. Indeed, 16 comparison of flow maps for several surfactant concentrations seems to indicate that the 17 dynamic interfacial tension is higher than the one expected (equilibrium), for surfactant 18 concentrations lower than one hundred times the critical micelle concentration. The esti-19 mated diffusion time of Tween 80 is compared to the droplet formation time at different 20 conditions. The choice of more appropriate dimensionless numbers to represent flow maps 21 is also discussed. 22
    Jiupeng Du, Nelson Ibaseta, Pierrette Guichardon. Generation of an O/W emulsion in a flow-focusing microchip: importance of wetting conditions and of dynamic interfacial tension. Chemical Engineering Research and Design, Elsevier, 2020, ⟨10.1016/j.cherd.2020.04.012⟩. ⟨hal-02799613⟩
    Journal: Chemical Engineering Research and Design
    Date de publication: 01-07-2020
    Auteurs:
    Liste des documents:
    Digital object identifier (doi): http://dx.doi.org/10.1016/j.cherd.2020.04.012
    Voir la publication sur Hal
  • 2020
    Kelly Ohanessian, Mathias Monnot, Philippe Moulin, Jean-Henry Ferrasse, Cristian Barca, et al.. Dead-end and crossflow ultrafiltration process modelling: Application on chemical mechanical polishing wastewaters. Chemical Engineering Research and Design, Elsevier, 2020, 158, pp.164-176. ⟨10.1016/j.cherd.2020.04.007⟩. ⟨hal-02892457⟩ Plus de détails...

    Dead-end and crossflow ultrafiltration process modelling: Application on chemical mechanical polishing wastewaters

    Dynamic simulation of ultrafiltration process is applied to the treatment of chemical mechanical polishing wastewater from microelectronic industry. The ultrafiltration of nanoparticles (NPs) contained in chemical mechanical polishing wastewater is modelled by using different mathematical equations, which are derived from the literature and optimized to the effluent and filtration modes (dead-end or crossflow). A series of ultrafiltration experiments at laboratory scale are carried out by using chemical mechanical polishing wastewater to optimize and validate the models. Complete dead-end and crossflow ultrafiltration models are developed to simulate the treatment performances of chemical mechanical polishing wastewater under dynamic full-scale and different operating conditions, thus including filtration and washing steps. Simulations show that the dead-end mode is not suitable for chemical mechanical polishing wastewater concentration higher than 100 mgNPs L-1 due to the too fast fouling time and to the high frequency of washing step. The high concentration of chemical mechanical polishing P wastewater (2600 mgNPs L-1) forces industries to use crossflow ultrafiltration to have a profitable process by controlling parameters such as the filtration/backwashing number of cycles, the needed filtering surface and the filtration flux.
    Kelly Ohanessian, Mathias Monnot, Philippe Moulin, Jean-Henry Ferrasse, Cristian Barca, et al.. Dead-end and crossflow ultrafiltration process modelling: Application on chemical mechanical polishing wastewaters. Chemical Engineering Research and Design, Elsevier, 2020, 158, pp.164-176. ⟨10.1016/j.cherd.2020.04.007⟩. ⟨hal-02892457⟩
    Journal: Chemical Engineering Research and Design
    Date de publication: 01-06-2020
    Auteurs:
    Digital object identifier (doi): http://dx.doi.org/10.1016/j.cherd.2020.04.007
    Voir la publication sur Hal
  • 2020
    Paul G. Chen, J Lyu, M Jaeger, M. Leonetti. Shape transition and hydrodynamics of vesicles in tube flow. Physical Review Fluids, American Physical Society, 2020, 5 (4), pp.043602. ⟨10.1103/PhysRevFluids.5.043602⟩. ⟨hal-02415320v2⟩ Plus de détails...

    Shape transition and hydrodynamics of vesicles in tube flow

    The steady motion and deformation of a lipid-bilayer vesicle translating through a circular tube in low Reynolds number pressure-driven flow are investigated numerically using an axisymmetric boundary element method. This fluid-structure interaction problem is determined by three dimen-sionless parameters: reduced volume (a measure of the vesicle asphericity), geometric confinement (the ratio of the vesicle effective radius to the tube radius), and capillary number (the ratio of viscous to bending forces). The physical constraints of a vesicle--fixed surface area and enclosed volume when it is confined in a tube--determine critical confinement beyond which it cannot pass through without rupturing its membrane. The simulated results are presented in a wide range of reduced volumes [0.6, 0.98] for different degrees of confinement; the reduced volume of 0.6 mimics red blood cells. We draw a phase diagram of vesicle shapes and propose a shape transition line separating the parachutelike shape region from the bulletlike one in the reduced volume versus confinement phase space. We show that the shape transition marks a change in the behavior of vesicle mobility, especially for highly deflated vesicles. Most importantly, high-resolution simulations make it possible for us to examine the hydrodynamic interaction between the wall boundary and the vesicle surface at conditions of very high confinement, thus providing the limiting behavior of several quantities of interest, such as the thickness of lubrication film, vesicle mobility and its length, and the extra pressure drop due to the presence of the vesicle. This extra pressure drop holds implications for the rheology of dilute vesicle suspensions. Furthermore, we present various correlations and discuss a number of practical applications. The results of this work may serve as a benchmark for future studies and help devise tube-flow experiments.
    Paul G. Chen, J Lyu, M Jaeger, M. Leonetti. Shape transition and hydrodynamics of vesicles in tube flow. Physical Review Fluids, American Physical Society, 2020, 5 (4), pp.043602. ⟨10.1103/PhysRevFluids.5.043602⟩. ⟨hal-02415320v2⟩
    Journal: Physical Review Fluids
    Date de publication: 23-04-2020
    Auteurs:
    Liste des documents:
    Digital object identifier (doi): http://dx.doi.org/10.1103/PhysRevFluids.5.043602
    Voir la publication sur Hal
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Archives récentes Archives

Soutenances de thèses et HDR

Actualités Archives
Mardi 16 Mars à 14h00 - Preparation of polyurea microcapsules calibrated in size and shell thickness by a microfluidic process for the absorption of ultraviolet / Soutenance de thèse Jiupeng DU
Doctorant : Jiupeng DU

Date de soutenance :  le mardi 16 mars à 14h00 en VISIO

Abstract : This thesis aims to exploit the advantages of microfluidics for the production of polyurea microcapsules. Because of its ability to produce drops with a very narrow size distribution, microfluidic emulsification shows great interest as the first step for rapid interfacial polymerisation. Although the literature on the production of drops in microchannels is abundant, commonly used organic solvents are limited to certain toxic hydrocarbon oils or ketones, as these solvents are very hydrophobic and therefore easy to emulsify in water.

The first part of the work concentrates on the feasibility of emulsifying two less hydrophobic green solvents (dibutyl adipate and n-butyl acetate) in water and study the different flow regimes within a hydrophilic flow-focusing microchannel of glass. The results show that the wetting of the walls by dibutyl adipate can be modified by adding a surfactant (Tween 80). However, the formation of the drops being much faster than the transfer of the surfactant to the interface of the drop being formed, concentrations much higher than the critical micellar concentration are necessary to avoid wetting of the walls by the dispersed phase and thus the appearance of disordered flow regimes. The behavior of the n-butyl acetate/water system is similar, but the comparison of the flow maps for the two systems raises the question of the choice of dimensional numbers for representing the transition between the dripping and jetting regimes.

In the second part, the addition of an interfacial polymerization within the emulsion formed by microfluidics is studied in detail. We aim to fabricate polyurea microcapsules calibrated in size and shell thickness containing octyl salicylate (OS). These microcapsules are used to study, for the first time, the influence of the shell thickness of microcapsules on their absorption efficiency against ultraviolet (UV) light. The results show that an increase of the concentration of isocyanate (HDB-LV or hexamethylene diisocyanate biuret) in the organic phase increases the shell thickness of the microcapsules, their encapsulation efficiency and very moderately their average absorbance. The average absorbance of the microcapsules is inversely proportional to the size of the microcapsules (for the same mass of OS). A theoretical model is proposed to estimate the average absorbance as a function of the mass fraction of HDB-LV in the organic phase and of the size of microcapsules. Finally, the concentration of amine (ethylenediamine) has been optimized to ensure the spherical shape of the microcapsules.

Jury:

Marc LEONETTI (CNRS, LRP), Rapporteur
Nathalie LE SAUZE (Univ Toulouse III), Rapportrice             
Christophe Alexandre SERRA (Univ Strasbourg), Examinateur
Stéphane VEESLER (CNRS, CINAM), Examinateur
Pierrette GUICHARDON (ECM, M2P2), Directrice      
Nelson IBASETA (ECM, M2P2), Codirecteur
Jean-Claude HUBAUD (Helioscience), invité
Bruno MONTAGNIER (Capsudev), invité
Mardi 17 Décembre 2019 - Eco-design of a Dry Cleaning Machine by Integration of a Membrane Process for Solvent Dehydration / Soutenance de thèse Oleksandr DIMITROV
Doctorant : Oleksandr DIMITROV               
  
Date de la soutenance :  le 17 décembre 2019 à 10h30, Amphi 3, Centrale Marseille. 

Résumé : la soutenance se tiendra à huit-clos

Jury: 
Denis ROIZARD                                    DR CNRS, LRGP, Nancy                             Rapporteur
Boris KOSOY                                        Professeur, ONAFT, Odessa                        Rapporteur
Ilham MOKBEL                                    MCF, Univ Lyon 1, Lyon                                 Examinatrice
Isabelle RASPO                                    CR CNRS, M2P2, Marseille                          Examinatrice
Sylvain MARC                                      PhD,  Arcane Industries, Géménos               Examinateur
Pierrette GUICHARDON                     Professeur ECM, Marseille                             Directrice de thèse
Evelyne NEAU                                     Professeur EM, Aix-Marseille Univ, Marseille   Invitée
Olivier BAUDOUIN                             Ingénieur, PROSIM, Labège                               Invité
Jacques JOSE                                      Professeur EM, Univ Lyon 1, Lyon                   Invité
Alfred TESTA                                       Dirigéant, Innovaclean, Géménos                     Invité